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Two main kinase signaling cascades exist: (1) ATMChk2 and (2) ATRChk1 pathways activated to induce cell cycle arrest

The autoimmune condition occurs in individuals whose bodies do not produce enough insulin and requires lifelong insulin therapy to regulate blood sugar levels

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Originally developed to help manage type 2 diabetes, these drugs are now widely used for both weight loss and blood-glucose control

The RPE has very important functions for keeping the retina alive and to enable photoreceptor cells to detect light